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Tey, S. L., et al. ‘Effects of Aspartame-, Monk Fruit-, Stevia- and Sucrose-Sweetened Beverages on Postprandial Glucose, Insulin and Energy Intake’. International Journal of Obesity (2005), vol. 41, no. 3, Mar. 2017, pp. 450–57. PubMed, https://doi.org/10.1038/ijo.2016.225.
Link: https://pubmed.ncbi.nlm.nih.gov/27956737/
Change in Insulin:
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Conclusions:
In conclusion, the consumption of calorie free beverages sweetened with non-nutritive sweeteners has minimal influences on total daily energy intake, glucose and insulin responses compared to a sucrose sweetened beverage in healthy lean males. It appears that the source of non-nutritive sweeteners (artificial or natural) does not differ in their effects on energy intake, postprandial glucose and insulin.
PDF: 📂 Media/PDFs/ijo.2016.225.pdf
| Endpoints | Exposures | Populations | General | People |
|---|---|---|---|---|
| #insulin | #artificial_sweeteners | #humans | #nutrition | |
| #blood_glucose | #overweight | #low_carb_talking_points | ||
| #obese | #novel_food | |||
| #processed_food | ||||
| #sugar | ||||
| #sugar_sweetened_beverages | ||||
| #hormones |
Ma, Jing, et al. ‘Effect of the Artificial Sweetener, Sucralose, on Gastric Emptying and Incretin Hormone Release in Healthy Subjects’. American Journal of Physiology. Gastrointestinal and Liver Physiology, vol. 296, no. 4, Apr. 2009, pp. G735-739. PubMed, https://doi.org/10.1152/ajpgi.90708.2008.
Link: https://pubmed.ncbi.nlm.nih.gov/19221011/
Hormonal Responses:
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Conclusions:
In conclusion, we have not been able to demonstrate that sucralose given by intragastric infusion stimulates GLP-1 or GIP release in humans or elicits a feedback response to slow gastric emptying. This implies that artificial sweeteners may have no therapeutic benefit in the dietary management of diabetes, other than as a substitute for carbohydrate.
PDF: 📂 Media/PDFs/ajpgi.90708.2008.pdf
| Endpoints | Exposures | Populations | General | People |
|---|---|---|---|---|
| #insulin | #artificial_sweeteners | #humans | #nutrition | |
| #blood_glucose | #low_carb_talking_points | |||
| #satiety | #novel_food | |||
| #processed_food | ||||
| #sugar | ||||
| #sugar_sweetened_beverages | ||||
| #hormones |