obsidian/🥙 Nutrition Vault/Artificial sweeteners and insulin.md
2024-06-28 02:13:12 -05:00

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Tey, S. L., et al. Effects of Aspartame-, Monk Fruit-, Stevia- and Sucrose-Sweetened Beverages on Postprandial Glucose, Insulin and Energy Intake. _International Journal of Obesity (2005)_, vol. 41, no. 3, Mar. 2017, pp. 45057. _PubMed_, https://doi.org/10.1038/ijo.2016.225.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/27956737/
**Change in Insulin:**
![[📂 Media/PDFs/Pasted image 20220222183613.png]]
**Conclusions:**
>In conclusion, the consumption of calorie free beverages sweetened with non-nutritive sweeteners has minimal influences on total daily energy intake, glucose and insulin responses compared to a sucrose sweetened beverage in healthy lean males. It appears that the source of non-nutritive sweeteners (artificial or natural) does not differ in their effects on energy intake, postprandial glucose and insulin.
**PDF:**
[[📂 Media/PDFs/ijo.2016.225.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** |
| -------------- | ---------------------- | --------------- | -------------------------- | ---------- |
| #insulin | #artificial_sweeteners | #humans | #nutrition | |
| #blood_glucose | | #overweight | #low_carb_talking_points | |
| | | #obese | #novel_food | |
| | | | #processed_food | |
| | | | #sugar | |
| | | | #sugar_sweetened_beverages | |
| | | | #hormones | |
****
Ma, Jing, et al. Effect of the Artificial Sweetener, Sucralose, on Gastric Emptying and Incretin Hormone Release in Healthy Subjects. _American Journal of Physiology. Gastrointestinal and Liver Physiology_, vol. 296, no. 4, Apr. 2009, pp. G735-739. _PubMed_, https://doi.org/10.1152/ajpgi.90708.2008.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/19221011/
**Hormonal Responses:**
![[📂 Media/PDFs/Pasted image 20220222184126.png]]
**Conclusions:**
>In conclusion, we have not been able to demonstrate that sucralose given by intragastric infusion stimulates GLP-1 or GIP release in humans or elicits a feedback response to slow gastric emptying. This implies that artificial sweeteners may have no therapeutic benefit in the dietary management of diabetes, other than as a substitute for carbohydrate.
**PDF:**
[[📂 Media/PDFs/ajpgi.90708.2008.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** |
| -------------- | ---------------------- | --------------- | -------------------------- | ---------- |
| #insulin | #artificial_sweeteners | #humans | #nutrition | |
| #blood_glucose | | | #low_carb_talking_points | |
| #satiety | | | #novel_food | |
| | | | #processed_food | |
| | | | #sugar | |
| | | | #sugar_sweetened_beverages | |
| | | | #hormones | |
****