obsidian/🛡️ Debate/Opponents/Sameer Dossani.md

Debate 1

"These principles disprove the idea that eating meat or saturated fat causes heart attacks." - Sameer Dossani

Analysis

1. "we care about heart disease, we don't care about cholesterol."
   1. ApoB is the causal agent (1).
   2. GWAS show ApoB is linearly associated across numerous mechanisms (2). !
   3. LDL-C as a proportional relationship to ASCVD risk (3). !
   4. LDL-C correlates with risk when other risk factors are optimized (4). !
   5. Discordance can explain the lack of association at lower LDL-C (5)
2. "cholesterol is necessary for life."
3. "heart disease is a modern phenomenon."
   1. Traditional populations still get ASCVD (6).
4. "there are non-western, historic populations that don't suffer from heart disease."
   1. The Maasai still get ASCVD(7).
   2. The Inuit still get ASCVD(8)(9).
   3. Inuit mummies still show ASCVD (10).

https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.118.034032

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Hilarious Argument

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