mirror of
https://gitlab.com/upRootNutrition/obsidian.git
synced 2025-06-16 18:05:13 -05:00
30 lines
No EOL
1.3 KiB
Markdown
Executable file
30 lines
No EOL
1.3 KiB
Markdown
Executable file
# Claim
|
|
|
|
>Seed oils are unhealthy because most lipids found in atheromas are oxidized.
|
|
|
|
## Rebuttal
|
|
|
|
This claim is merely [[mechanistic speculation]], and is an example of the [[ecological fallacy]]. Essentially, it is being posited that merely because atherosclerotic plaques contain high proportions of oxidized [[linoleic acid]] (LA), that said LA must have caused the atherosclerotic plaque to begin with. It is true that plaques contain very high proportions of oxidized LA [(1)](https://pubmed.ncbi.nlm.nih.gov/10397689/)[(2)](https://pubmed.ncbi.nlm.nih.gov/8632720/). However, we must remember the pathophysiology of [[atherosclerosis]], which involves native [[low-density lipoproteins]] particles being irreversibly bound to [[proteoglycans]] in the [[subendothelial space]] [(3)](https://pubmed.ncbi.nlm.nih.gov/9637699/)[(4)](https://pubmed.ncbi.nlm.nih.gov/27472409/). Once bound, oxidation is inevitable. It's unclear that restricting seed oils will actually lead to reduced oxidized lipids in the plaque.
|
|
|
|
---
|
|
|
|
## References
|
|
|
|
1. https://pubmed.ncbi.nlm.nih.gov/10397689/
|
|
2. https://pubmed.ncbi.nlm.nih.gov/8632720/
|
|
3. https://pubmed.ncbi.nlm.nih.gov/9637699/
|
|
4. https://pubmed.ncbi.nlm.nih.gov/27472409/
|
|
|
|
---
|
|
|
|
# Hashtags
|
|
|
|
#claims
|
|
#ecological_fallacy
|
|
#heart_disease
|
|
#cardiology
|
|
#low-density_lipoproteins
|
|
#mechanistic_speculation
|
|
#proteoglycans
|
|
#seed_oils
|
|
#hyperblog |