Points:

All points must be taken in the context that the sample population was self-selected and paying.
They counted improvements sustained by metformin toward their reversal statistic of 32.5%.
Complete remission without drugs was only 6.7% among completers, and 4.7% ITT (Table 1).
45% of the participants started GLP1 agonists and another 10% increased their dosage (Fig. 3A).
Hba1c essentially returned to baseline despite subjects maintaining 50% of weight loss.
- Likely due to not reinstating medications.
- Difficult to make inferences about insulin sensitivity either way.
LDL was changed by 4.6 mg/dL, which is about half as much as is expected from going from the lowest to highest cholesterol intake.
- Not sure why we care about HDL, TG, or ApoA-1.