https://pubmed.ncbi.nlm.nih.gov/26109578/ "Reviewed studies were heterogeneous and lacked the methodologic rigor to draw any conclusions regarding the effects of dietary cholesterol on CVD risk. Carefully adjusted and well-conducted cohort studies would be useful to identify the relative effects of dietary cholesterol on CVD risk." https://pubmed.ncbi.nlm.nih.gov/1534437/ "Possible reasons for the hyperbolic shape of the relationship between change in serum cholesterol and added dietary cholesterol, mechanisms for individual responsiveness to dietary cholesterol, and important implications regarding interpretation of prior studies and public health issues are discussed." https://pubmed.ncbi.nlm.nih.gov/30596814/ "The change in dietary cholesterol was positively associated with the change in LDL-cholesterol concentration. The linear and MM models indicate that the change in dietary cholesterol is modestly inversely related to the change in circulating HDL-cholesterol concentrations in men but is positively related in women. The clinical implications of HDL-cholesterol changes associated with dietary cholesterol remain uncertain." https://pubmed.ncbi.nlm.nih.gov/14764421/ "The possibility has been discussed that administration of inhibitors of cholesterol synthesis may reduce the prevalence of Alzheimer disease. No firm conclusions can, however, be drawn from the studies presented thus far. In the present review, the most recent advances in our understanding of cholesterol turnover in the brain is discussed." https://jamanetwork.com/journals/jama/fullarticle/2728487 #disease #coronary_heart_disease #cardiovascular_disease #dietary_cholesterol #mental_health #nutrition #blood_lipids