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🥙 Nutrition Vault/Matt's presentation on legumes and CVD.md Executable file
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**Notes:**
- Mozaffarian et al 2016
- Cardiovascular Health
**Blood Pressure:**
- Jayalath et al. 2014
- Legume and blood pressure meta
- >2 servings/day from one month to one year
- Stat-sig reduction in SBP
- Kou el al. 2017 & Mosallenezhad et al. 2021
- 25g/day of soy
- Stat-sig reduction in SBP an DBP
**Soy intervention doses and BP:**
![[Pasted image 20220306135116.png]]
**Serum Lipids:**
- Bazzano et al. 2011
- 1 serving/day non-soy legumes
- 3-8 weeks
- Stat sig reductions in TC and LDL
- Tokede et al. 2015
- 30g/day protein from soy products
- Stat sig reduction in LDL
**Blood Glucose:**
- Haafix et al. 2021
- Legume-based snacks/meals.
- Suggested benefit from legumes
- Stat sig reduction for BG and A1C in diabetics
- Asbaghi et al. 2021
- Stat sig for soy beans
**CVD Risk Factors:**
- Hosseinpour-Nazi et al. 2015
- 31 diabetics for 8 weeks, w/ 4 week washout
- 2 servings of legumes subbing for red meat
- Stat sig benefits to LDL, TG, BG, and insulin with legumes
- Azadbakt et al. 2008
- 41 diabetics for 4 years
- Replacing 1/2 of animal protein calories with legumes
- Stat sig reduction in TC, TG, BG, and CRP, and DBP
**Mendelian Randomization Markers:**
![[Pasted image 20220306143219.png]]
**Cohort Studies:**
- Viguillouk et al 2019
- 28 cohorts
- 0-225g/day
- Stat sig 8%A reduction in CVD incidence
**Meta 1 Breakdown:**
![[Pasted image 20220306144016.png]]
**Meta 2 Breakdown:**
![[Pasted image 20220306144231.png]]
**Meta 3 Breakdown:**
![[Pasted image 20220306144544.png]]
**Meta 4 Breakdown:**
![[Pasted image 20220306145003.png]]
| **Endpoints** | **Exposures** | **Populations** | **General** | People |
| --------------- | ------------- | --------------- | -------------- | ------------ |
| #cardiovascular_disease | #legumes | #humans | #disease | #matt_madore |
| #coronary_heart_disease | #soy | #multinational | #plant_foods | |
| #blood_glucose | | | #plant_protein | |
| #blood_lipids | | | | |
| #blood_pressure | | | | |
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