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🏛️ Home/Virta.md
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# Points:
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- All points must be taken in the context that the sample population was self-selected and paying.
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- They counted improvements sustained by metformin toward their reversal statistic of 32.5%.
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- Complete remission without drugs was only 6.7% among completers, and 4.7% ITT (Table 1).
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- 45% of the participants started GLP1 agonists and another 10% increased their dosage (Fig. 3A).
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- Hba1c essentially returned to baseline despite subjects maintaining 50% of weight loss.
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- Likely due to not reinstating medications.
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- Difficult to make inferences about insulin sensitivity either way.
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- LDL was changed by 4.6 mg/dL, which is about half as much as is expected from going from the lowest to highest cholesterol intake.
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- Not sure why we care about HDL, TG, or ApoA-1.
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