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Saito, Eiko, et al. Association between Meat Intake and Mortality Due to All-Cause and Major Causes of Death in a Japanese Population. _PloS One_, vol. 15, no. 12, 2020, p. e0244007. _PubMed_, https://doi.org/10.1371/journal.pone.0244007.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/33320898/
**Population Characteristics:**
![[Pasted image 20220213220316.png]]
**Disease Risk (Men):**
![[Pasted image 20220213220410.png]]
**Adjustment Model:**
![[Pasted image 20220213220546.png]]
**Disease Risk (Women):**
![[Pasted image 20220213220456.png]]
**Adjustment Model:**
![[Pasted image 20220213220603.png]]
**Disease Risk by Age:**
![[Pasted image 20220213220831.png]]
**Adjustment Model:**
![[Pasted image 20220213220841.png]]
**Conclusion:**
>In conclusion, we found that greater consumption of unprocessed and processed red meats is associated with higher mortality risk. Compared with red meat, other dietary components, such as fish, poultry, nuts, legumes, low-fat dairy products, and whole grains, were associated with lower risk. These results indicate that replacement of red meat with alternative healthy dietary components may lower the mortality risk.
**Notes:**
**PDF:**
[[📂 Media/PDFs/journal.pone.0244007.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** | |
| ------------------ | ------------- | --------------------------- | -------------------- | ---------- | --- |
| #cancer | #red_meat | #japan_public_health_center | #mortality | | |
| #cardiovascular_disease | #animal_foods | #japan | #disease | | |
| #all_cause_mortality | #beef | #men | #healthy_user_bias | | |
| #stroke | #pork | #women | #low_carb_talking_points | | |
| #colorectal_cancer | #chicken | | #nutrition | | |
| | | | #dose_response | | |
****
Pan, An, et al. Red Meat Consumption and Mortality: Results from 2 Prospective Cohort Studies. _Archives of Internal Medicine_, vol. 172, no. 7, Apr. 2012, pp. 55563. _PubMed_, https://doi.org/10.1001/archinternmed.2011.2287.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/22412075/
**Men Characteristics:**
![[Pasted image 20220213212514.png]]
**Women Characteristics:**
![[Pasted image 20220213212533.png]]
**All Cause Mortality:**
![[Pasted image 20220213212640.png]]
**Adjustment Model:**
![[Pasted image 20220213212704.png]]
**CVD Mortality:**
![[Pasted image 20220213212809.png]]
**Adjustment Model:**
![[Pasted image 20220213212829.png]]
**Cancer Mortality:**
![[Pasted image 20220213212843.png]]
**Adjustment Model:**
![[Pasted image 20220213212857.png]]
**Dose-Response:**
![[Pasted image 20220213212948.png]]
**Adjustment Model:**
![[Pasted image 20220213213007.png]]
**Substitution Analysis:**
![[Pasted image 20220213213138.png]]
**Conclusion:**
![[Pasted image 20220213213202.png]]
**Notes:**
Healthy-user bias was mildly present
**PDF:**
[[📂 Media/PDFs/ioi110027_555_563.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** | |
| ------------- | --------------- | ------------------------------------ | ---------------------- | --------------- | --- |
| #cancer | #red_meat | #nurses_health_study | #mortality | #walter_willett | |
| #cardiovascular_disease | #animal_foods | #health_professionals_followup_study | #disease | #frank_hu | |
| #all_cause_mortality | #meat | #united_states | #substitution_analyses | | |
| | #processed_meat | | #nutrition | | |
| | | | #cohort_studies | | |
****
Zheng, Yan, et al. Association of Changes in Red Meat Consumption with Total and Cause Specific Mortality among US Women and Men: Two Prospective Cohort Studies. _BMJ (Clinical Research Ed.)_, vol. 365, June 2019, p. l2110. _PubMed_, https://doi.org/10.1136/bmj.l2110.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/31189526/
**Red Meat and Mortality Risk:**
![[Pasted image 20220214171128.png]]
**Substitution Analysis:**
![[Pasted image 20220214171156.png]]
**Conclusions:**
>Increases in red meat consumption, especially processed meat, over eight years were associated with a higher risk of death in the subsequent eight years in US women and men. Increased consumption of healthier animal or plant foods was associated with a lower risk of death compared with red meat consumption. Our analysis provides further evidence to support the replacement of red and processed meat consumption with healthy alternative food choices.
**PDF:**
[[📂 Media/PDFs/bmj.l2110.full.pdf]]
**Supplements:**
[[📂 Media/PDFs/zhey047253.ww1.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** |
| ------------------------ | --------------- | ------------------------------------ | ------------- | --------------- |
| #all_cause_mortality | #red_meat | #nurses_health_study | #disease | #walter_willett |
| #cardiovascular_disease | #processed_meat | #health_professionals_followup_study | #nutrition | #frank_hu |
| #neurodegerative_disease | #meat | #humans | #epidemiology | #yan_zheng |
| | #nuts | #male_health | #mortality | |
| | #poultry | #female_health | | |
| | #fish | | | |
| | #dairy | | | |
| | #eggs | | | |
| | #legumes | | | |
| | #whole_grains | | | |
| | #vegetables | | | |
****
https://zbib.org
**Link:**
****
**Conclusions:**
>
**PDF:**
[[📂 Media/PDFs/Red_meat_consumption_and_allcause_and_cardiovascular_mortality-_results_from_the_UK_Biobank_study.pdf]]
**Supplements:**
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** |
| ------------- | ------------- | --------------- | ----------- | ---------- |
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****