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🥙 Nutrition Vault/Conjugated linoleic acid and body composition.md Normal file
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Onakpoya, Igho J., et al. ‘The Efficacy of Long-Term Conjugated Linoleic Acid (CLA) Supplementation on Body Composition in Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Clinical Trials’. _European Journal of Nutrition_, vol. 51, no. 2, Mar. 2012, pp. 127–34. _PubMed_, https://doi.org/10.1007/s00394-011-0253-9.
**Link:**
https://pubmed.ncbi.nlm.nih.gov/21990002/
**CLA and Body Composition:**
![[Pasted image 20220220102348.png]]
**Dose-Response:**
![[Pasted image 20220220102405.png]]
**Conclusions:**
>The evidence from RCTs fails to convincingly demonstrate that CLA supplementation generates any clinically relevant effects on body composition on the long term.
**PDF:**
[[📂 Media/PDFs/s00394-011-0253-9.pdf]]
| **Endpoints** | **Exposures** | **Populations** | **General** | **People** |
| --------------- | -------------- | --------------- | ----------- | ---------- |
| #anthropometics | #conjugated_linoleic_acid | #humans | #nutrition | |
| #weight_loss | #linoleic_acid | | #disease | |
| #weight_gain | | | #overweight | |
| | | | #obesity | |
****