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28 lines
1.3 KiB
Markdown
28 lines
1.3 KiB
Markdown
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# Low-Density Lipoproteins
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Low-density lipoprotein (LDL) are types of [[lipoproteins]] that plays a crucial role in cholesterol transport within the human body. Often, and somewhat imprecisely, referred to as "bad cholesterol", LDL is a complex of lipids and proteins that carries [[cholesterol]] from the liver to various tissues throughout the body.
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Structurally, LDL particles consist of:
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- A core of cholesterol esters and triglycerides.
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- An outer layer of phospholipids and unesterified cholesterol.
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- A single apolipoprotein B-100 molecule.
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LDL particles are formed in the bloodstream as very-low-density lipoproteins (VLDL) lose triglycerides through the action of lipoprotein lipase. As this process continues, VLDL particles become increasingly dense, eventually forming LDL.
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However, elevated levels of LDL in the bloodstream are associated with an increased risk of cardiovascular disease, particularly [[atherosclerosis]]. This is because excess LDL can penetrate the arterial wall and become [[oxidized low-density lipoproteins]], triggering [[inflammation]] that leads to plaque formation.
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---
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# Hashtags
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#lipids
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#cholesterol
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#low-density_lipoproteins
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#oxidized_low-density_lipoproteins
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#dietary_fat
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#apob
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#cardiology
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#heart_disease
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#heart_attack
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#hyperblog
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