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40 lines
1.7 KiB
Markdown
40 lines
1.7 KiB
Markdown
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# Debate 1
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>"These principles disprove the idea that eating meat or saturated fat causes heart attacks." - Sameer Dossani
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## Analysis
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1. **"we care about heart disease, we don't care about cholesterol."**
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1. ApoB is the causal agent [(1)](https://pubmed.ncbi.nlm.nih.gov/32203549/).
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2. GWAS show ApoB is linearly associated across numerous mechanisms [(2)](https://pubmed.ncbi.nlm.nih.gov/30694319/). ![[Pasted image 20220628124254.png]]
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3. LDL-C as a proportional relationship to ASCVD risk [(3)](https://pubmed.ncbi.nlm.nih.gov/27673306/). ![[Pasted image 20220628124445.png]]
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4. LDL-C correlates with risk when other risk factors are optimized [(4)](https://pubmed.ncbi.nlm.nih.gov/29241485/). ![[Pasted image 20220628124922.png]]
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5. Discordance can explain the lack of association at lower LDL-C [(5)](https://pubmed.ncbi.nlm.nih.gov/15296705/)
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2. **"cholesterol is necessary for life."**
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3. **"heart disease is a modern phenomenon."**
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1. Traditional populations still get ASCVD [(6)](https://pubmed.ncbi.nlm.nih.gov/23489753/).
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4. **"there are non-western, historic populations that don't suffer from heart disease."**
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1. The Maasai still get ASCVD[(7)](https://pubmed.ncbi.nlm.nih.gov/5007361/).
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2. The Inuit still get ASCVD[(8)](https://pubmed.ncbi.nlm.nih.gov/2206175/)[(9)](https://pubmed.ncbi.nlm.nih.gov/12535749/).
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3. Inuit mummies still show ASCVD [(10)](https://pubmed.ncbi.nlm.nih.gov/31880790/).
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https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.118.034032
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![[Pasted image 20220628135128.png]]
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---
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# Hilarious Argument
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![[📂 Media/Images/Pasted image 20230723135007.png]]
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---
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# Hashtags
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#debate
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#debate_opponents
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#clowns
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#clownery
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#LDL
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#cardiovascular_disease
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